biodistribution study japan

what does he mean by long time? No traditional pharmacokinetic or biodistribution studies have been performed with the vaccine candidate BNT162b2. Why the confusion? Keywords: Radioactivity was detected in most tissues from the first time point (0.25 h) and results support that injections site and the liver are the major sites of distribution. Sunlight also has other benefits besides making vitamin D. Use time-restricted eating and eat all your meals for the day within a six- to eight-hour window. Even my doctor, who is against it, could not tell me public sources. Genotoxicity of 1,3-butadiene and its epoxy intermediates. I thought this would be an easy blog to write, cut and dry. All of these risk factors have something in common: Theyre all associated with mitochondrial dysfunction. Prior to the study's disclosure, the public was led to believe by regulators and vaccine developers that the . It is important that your sauna is hot enough (around 170 degrees Fahrenheit) and does not have high magnetic or electric fields. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. The greatest mean concentration was found remaining in the injection site at each time point in both sexes. 2015;99(23):99079922. The biodistribution study obtained by Bridle showed that the lipid nanoparticles in the vaccine did not remain . Playing Hardball in Government and Politics, Nuclear War At the Abyss of Mass Extermination, Pfizer Bio-Distribution Study Submitted to the Japanese Government, Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizers biodistribution study from the Japanese regulatory agency. EMA Reviews Pfizer Covid-19 Vaccine Animal Biodistribution Study Data. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. In response to information not being available on the internet, a Citizen petition to the FDA was filed by 27 prominent health experts and scientists on June 1, 2021, requesting proper pharmacokinetic and biodistribution safety studies be revealed or conducted by the vaccine manufacturers. 22 23 24 25 Janssen told The BMJ its covid-19 vaccine leverages the same technology as its Ebola vaccine, which received licensure last June. Documents obtained from Japanese regulatory agency reveal that Pfizer biodistribution studies showed that mRNA and spike proteins circulate widely throughout the body. *, o LNP=LipoNanoParticle which carries the mRNA, o LC-MS/MS is liquid chromatography with tandem mass spectrometry. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. While all of this is highly problematic, there is help. eCollection 2015. Methods This is a . Perhaps the attached study will be helpful to her. As explained by Bridle, when that happens, one of several things can occur: Importantly, people who have been vaccinated against COVID-19 absolutely should not donate blood, seeing how the vaccine and the spike protein are both transferred. At first glance, this information seems relatively straightforward. Brief Summary: The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants. 2. As a public-health body safeguarding medicines in the European Union (EU), EMA only recommends approval of a vaccine for COVID-19 after a thorough evaluation demonstrating the same high . Its past time to #RevoketheEUA https://t.co/ZdeHCKXyPb, BREAKING: Dr. Byram Bridle sent me his report: 'Why Parents, Teens, and Children Should Question the COVID-19 Vaccine'He's an Associate Professor of Viral Immunology at the University of Guelph who brought attention to the Pfizer Japanese study. He explained that critical information has recently been discovered that centers around spike proteinsa crucial element in both the SARS-CoV-2 virus and the COVID-19 vaccines. So by vaccinating people, we are inadvertently inoculating them with a toxin.. As we reported last June 14, Bridle received a copy of a Japanese biodistribution study, which had been withheld from the public, as a result of a freedom of information request made to the Japanese government for data from Pfizer. According to Bridle, the discovery also has implications for breastfeeding infants and severe consequences for people for whom the SARS-CoV-2 virus is not a high-risk pathogen, including all children. Prions are membrane proteins and when they misfold, they form crystals in the cytoplasm resulting in prion disease. The site is secure. Here in fact he spells out that the Japanese Pfizer biodistribution studies have found a high concentration of the Lipid Nanoparticles in the ovaries--a known result to Pfizer and the FDA . Disclaimer. . For an LNP-mRNA vaccine, DNA vaccine, or recombinant virus vaccine, a biodistribution study with the SARS-CoV-2 vaccine candidate is generally needed. its important. The author, Pankaj Prasun, points out that the virus impact on mitochondria helps explain why COVID-19 is so much deadlier for older people, the obese, and those with diabetes, high blood pressure and heart disease. Change), You are commenting using your Twitter account. Japanese Biodistribution study that Dr. Byram Bridle warned about showing that lipid-nano particles, the mRNA & thus possible spike bio-accumulated in distant tissue & organs based on rat model; Table Bridle was pilloried by all, the media, his insane putrid University colleagues etc. Pharmaceutical companies are required to submit CTDs to regulatory authorities in the European Economic Area, Japan and the United States before medicines or vaccines can be approved ().Pfizer . The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Why are these questions surfacing now? When an immune response is launched against the spike protein, the virus stops infecting the body. In addition, no findings on vital organ functions have been recorded in the repeat dose toxicology studies. High Mutational Heterogeneity, and New Mutations in the Human Coagulation Factor V Gene. Remember to check the date when the fact-check you are reading was published before sharing it. So, by vaccinating people, we are inadvertently inoculating them with a toxin. The effective dose was 0.0705 mSv/MBq. Its very disconcerting. Information about the cons of the vaccines is very difficult to find. The study has been supported financially by the Japan Agency for Medical Research and Development and Kitasato Institute. The biodistribution was also studied in rats, using radiolabeled LNP and luciferase modRNA (study 185350. In 2020, Bridle was awarded a $230,000 government grant for research on COVID vaccine development. It is important to pay attention to what is going on here. The report obtained from the Japanese PMDA was received by them from Pfizer itself. And yet Dr. Byram Bridle and Dr. Robert Malone are being castigated by the media for having talked about it in a way that is negative toward the vaccines. Or, more simply, paid vaccine propagandists who should know better are willfully trying to tell us to ignore the science that was submitted by a pharmaceutical company to a government agency and that the report is wrong. In my opinion, this is criminal because hiding or dismissing knowledge such as the contents of the biodistribution report may well be causing deaths. Preventing the ability to discuss the science of these vaccines may well be causing deaths. Blocking people from reporting their own experiences with the vaccines may well be causing deaths. Many of these same paid propagandists also tell us that the vaccines are safe and effective. This actually is a crime. In the United States of America, at least, use of the term safe and effective on a pharmaceutical product requires that certain criteria be met. Those criteria have not been met for any of the COVID-19 vaccines. All of the COVID-19 vaccines are still undergoing testing. Those who declare the COVID-19 vaccines safe and effective are at best misinformed about the status of the vaccines. At worst, they are outright lying to us. Thus, the absence of safety pharmacology studies is endorsed by the CHMP, Committee for Medicinal Products for Human Use. If you would like to help raise awareness of the facts surrounding children and COVID19 vaccines, please share. In short, when you get the COVID-19 vaccine, you are being injected with an agent that instructs your body to produce the bioweapon in its own cells. Please send me all info on any new updates. This is about as diabolical as it gets. Rightly, Bridle is extremely troubled about the current drive to vaccinate children against COVID-19, recently stating insufficient evidence exists to claim the benefits outweigh the risk of vaccinating the younger population. Production and hosting by Elsevier B.V. All authors declare that they have no competing interests. Until recently, the opinion has been that these vaccines function like traditional vaccines and remain near the injection site. Read our disclaimer for details. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizers biodistribution study from the Japanese regulatory agency. In what organs can you find the vaccine? This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. That same research also establishes that the spike protein alone is almost entirely responsible for damage to the cardiovascular system if circulating in the body. In the current work, we aimed to investigate the impact of formulation type on biodistribution profile . Please enable it to take advantage of the complete set of features! You are transferring the vaccine itself, as well as the spike protein, which could result in bleeding and/or blood clots in your child. Pharmacokinetics Pharmacokinetic parameters are not evaluated in this study. Study: Adverse events following COVID-19 virus vaccination in Japanese young population: The first cross-sectional study conducted by a questionnaire survey after the first-time-injection. Brindle, who stated the importance of sharing this new information openly, recently visited On Point with Alex Pierson and spoke at length on the scary situation facing humanity as the push to vaccinate the global population against SARS-CoV-2 gains momentum. In Japan, 10 fatal cases (five men and women) have been reported to date. The designers of the COVID-19 vaccines expected the contents of a jab to remain in the muscular tissue where they were injected, usually an arm. This assumption was wrong. A study document obtained from the Japanese regulatory agency shows that the vaccine contents enter the bloodstream and travel to the various organs.Lab animals injected with purified spike protein into their bloodstream developed cardiovascular problems, and the spike protein was also demonstrated to cross the blood brain barrier and cause damage to the brain. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Parkinsons disease is a prion disease that has been traced back to prions originating in the spleen, that then travel up to the brain via the vagus nerve. Spike protein does not attack anything, it only aims to activate the immune response, it is not the same as coronavirus spike protein and after vaccination, it is created in a dose 100 thousand times lower than in viral infection. (11 subjects out of 13 had S-protein in blood. Time-restricted eating will upregulate autophagy, while sauna therapy, which upregulates heat shock proteins, will help refold misfolded proteins and also tag damaged proteins and target them for removal. Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. 2011 Oct;17(10):881-90. doi: 10.1089/acm.2010.0481. Women have reported changes in menstruation after taking mRNA vaccines. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizer's biodistribution study from the Japanese regulatory agency. The first section is labeled: SARS-CoV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 Summary of pharmacokinetic study Increased oxidative stress may lead to endothelial dysfunction and aggravate systemic and local inflammation, thus contributing to acute lung injury, cytokine storm, and thrombosis seen in severe COVID-19 illness , A recent algorithm showed that majority of SARS-CoV-2 genomic and structural RNAs are targeted for mitochondrial matrix. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Whats more, TrialSite News reports6 that Pfizer documents submitted to the European Medicines Agency [EMA] reveal the company did not follow industry-standard quality management practices during preclinical toxicology studies as key studies did not meet good laboratory practice (GLP)., Neither reproductive toxicity nor genotoxicity (DNA mutation) studies were performed, both of which are considered critical when developing a new drug or vaccine for human use. It only looked at where the lipid nanoparticles go. It is a toxin that can cause damage in our body if it gets into circulation. What is the clinical outcome? Theranostics. The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as research continues to be done. Genetics Genetics (specified analyses) are not evaluated in this study. It is a toxin that can cause damage in our body if it gets into circulation. 2018;7(1):7886. Very often, the damage is caused by the immune system going on the attack, damaging blood vessel walls, and removing several of the anti-clotting mechanisms. The end result can be lethal, and this chain of events is exactly what these COVID-19 vaccines are setting into motion. Adams AJ, LaBonte JP, Ball ML, Richards-Hrdlicka KL, Toothman MH, Briggs CJ. Additionally, the EMA document states, "Biodistribution: Several literature reports indicate that LNP-formulated RNAs can distribute rather nonspecifically to several organs such as spleen, heart, kidney, lung and brain. The biodistribution of hybrid nanostructures is a major subject of current nanomedical research. Additionally, according to Bridle, an alarming study not yet accepted for publication that initially attempted to verify that antibodies from the vaccine get transferred through breast milk (suggesting some protection for babies), instead inadvertently discovered the mRNA vaccine spike proteins are transferred through the breast milk, thus passing the COVID-19 vaccine vector itself into breastfeeding infants. When in circulation, the spike protein can bind to the receptors that are on our platelets and the cells that line our blood vessels. Likewise, research within thescientific community also reveals various cardiovascular and heart problems, bleeding, and clotting when studying the disease in humans. Explanation: When you receive the covid vaccine, it will not impair the function of your ovaries, just as the coronavirus will not. Luciferase signals at the injection sites, most likely reflecting distribution to the lymph nodes draining the injection sites, peaked 6h post injection with signals of approximately 10 000 times of buffer control animals. The "Japanese biodistribution study," referenced in the online article appears to be a Japanese translation of a Pfizer toxicology and biodistribution study, which shows nothing like what is being claimed. Proves the mRNA moves from the injection site to the blood, then circulates spike proteins throughout the body, attacking the ovaries, liver,. In addition, mitochondrial damage leads to inappropriate and persistent inflammation.

Dangerous Animals In El Paso, Texas, Debarge Family Abuse, Emergetechnology Amita, Panera Beverage Subscription, Facetime Pick Up Lines, Articles B